专利名称：Methods for in vivo delivery of substantially water insoluble pharmacologically active
agents and compositions useful therefor
发明人：Neil P. Desai,Patrick Soon-Shiong,Paul A.
Sandford,Mark W. Grinstaff,Kenneth S.
Suslick
申请号：US08/023698
申请日：19930222
公开号：US05439686A
s.b.polo公开日：
19950808
专利内容由知识产权出版社提供
摘要：In accordance with the present invention, there are provided compositions for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug taxol) in which the pharmacologically active agent is delivered in a soluble form or in the form of suspended particles. In particular, the soluble form may comprise a solution of pharmacologically active agent in a biocompatible dispersing agent contained within a protein walled shell. Alternatively, the protein walled shell may contain particles of taxol. In another aspect, the suspended form comprises particles of pharmacologically active agent in a biocompatible aqueous liquid.
申请人：VIVORX PHARMACEUTICALS, INC.
代理人：Stephen E.Pretty, Schroeder, Brueggemann & Clark Reiter
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