大众新辉腾
中国医学影像学杂志2019年第27卷第5期影像技术学•论著
PET-MR与PET-CT显像中不同器官18F-FDG阳性病变SUV max的比较李灿,徐白萱,刘家金,富丽萍*
解放军总医院核医学科,北京100853;*通讯作者富丽萍 flp39@163
【摘要】目的探讨PET-MR与PET-CT在不同器官部位病变最大标准化摄取值(SUV max)的差异,评价PET-MR SUV max对不同器官18F-脱氧葡萄糖(18F-FDG)阳性病变定量诊断的能力。资料与方法回顾性分析以肿瘤相关主诉就诊,且同一天先后接受PET-CT和PET-MR检查的150例患者,两种检查时间间隔25~45 min。选取18F-FDG阳性病灶最大层面手动勾画感兴趣区,获得采用PET-MR测得的最大标准化摄取值(SUV max_MRI)与采用PET-CT测得的最大标准化摄取值(SUV max_CT),将经病理或临床确诊的18F-FDG阳性病灶分为6组(头颈部、肺部、肝脏、胰腺、胃肠道和骨骼)。分析2个成像系统SUV max的相关性和一致性。结果纳入6组的112个18F-FDG阳性病灶,分布于头颈部(15例)、肺部(15例)、肝脏(31例)、胰腺(21例)、胃肠道(11例)、骨骼(19例)。6组数据SUV max_MRI与SUV max_CT均呈高度正相关(r=0.96、0.97、0.96、0.95、0.94、0.91,P<0.05)。SUV max_MRI与SUV max_CT之间,数据最大变异出现在肺部(0.16),其次为头颈部(0.13),其他变异依次为胃肠道(0.11)、肝脏(0.08)、骨骼(0.03)和胰腺(0.02)。结论18F-FDG PET-MR可提供可靠的定量诊断信息用于肿瘤患者的临床评估。但SUV max数据间最大的差异出现在肺部病变,临床工作中对于肺部病灶定量分析仍需谨慎。
【关键词】肿瘤;正电子发射断层显像术;体层摄影术,X线计算机;磁共振成像;氟脱氧葡萄糖F18
【中图分类号】R73;R445.6 【DOI】10.3969/j.issn.1005-5185.2019.05.015
高性价比中级车开车的技巧Comparison of SUVmax Between 18F-FDG Positive Lesions in Different Organs of PET-MR and PET-CT Imaging
广州本田飞度报价车源信息LI Can, XU Baixuan, LIU Jiajin, FU Liping*
Department of Nuclear Medicine, PLA General Hospital, Beijing 100853, China; *Address Correspondence to:FU Liping; E-mail: flp39@163
【Abstract】Purpose To explore the difference of maximum SUV (SUV max) of lesions between PET-MR and PET-CT in different organs, and to assess the ability of PET-MR SUV max to quantitatively diagnose 18F-deoxyglucose (18F-FDG) positive lesions in different organs. Materials and Methods150 patients who were treated with tumor-associated chief complaint and successively underwent PET-CT and PET-MR examinations on the same day were retrospectively analyzed. The interval between the two examinations was 25 to 45 minutes. 18F-FDG positive lesion with maximum area was opted to manually delineate ROI, and the maximum standardized uptake value (SUV max_
MRI) measured by PET-MR and that (SUV max_CT) measured by PET-CT were obtained. Pathologically or clinically diagnosed 18F-FDG positive lesions were divided into 6 groups (head and neck, lung, liver, pancreas, gastrointestinal tract and bone). The correlation and consistency of SUV max of the two imaging systems were analyzed. Results112 18F-FDG positive lesions of the 6 groups were included in the study. They were distributed in the head and neck (15 cases), lung (15 cases), liver (31 cases), pancreas (21 cases), gastrointestinal tract (11 cases), and bone (19 cases). The SUV max_MRI and SUV max_CT in the 6 groups of data were highly correlated (r=0.96, 0.97, 0.96, 0.95, 0.94 and 0.91, respectively, P<0.05). The largest data variability, as compared between the SUV max_MRI and SUV max_CT, occurred in the lungs (0.16), followed by the head and neck (0.13), then gastrointestinal tract (0.11), livers (0.08), bone (0.03) and pancreas (0.02). Conclusion18F-FDG PET-MR provides reliable quantitative diagnostic information for clinical evaluation of cancer patients. However, the biggest difference between the SUV max data lay in the lung lesions, suggesting that quantitative analysis of lung lesions remains to be a cautious practice in clinic.
【Key words】Neoplasms; Positron-emission tomography; Tomography, X-ray computed; Magnetic resonance imaging; Fluorodeoxyglucose F18
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Chinese Journal of Medical Imaging, 2019, 27 (5): 379-384
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